An active metabolite of 8-chloro cAMP; its accumulation is associated with inhibition of cell growth, decreases in endogenous ATP levels, and a reduction in RNA, but not DNA, synthesis in patient-derived multiple myeloma cells; inhibits topoisomerase II-α-dependent relaxation of supercoiled pUC19 DNA at 1.5-8 mM in K562 cells; reduces topoisomerase II-α-catalyzed ATP hydrolysis by 50% at 1 mM in K562 cells